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Clinical Study of Transcriptome-based Diagnostic Biomarker for Acute Febrile Illness

NCT06552975 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 900

Last updated 2024-08-14

No results posted yet for this study

Summary

Acute febrile illness is the main cause of outpatient visits，and bacterial and viral infections remains the most common cause. The diagnosis of infection is still based on symptoms and traditional techniques, resulting in overuse of antibacterial drugs or delay in treatment. The signature of host transcripts has a potential to reveal different modes of host-pathogen interaction and may serve as a biomarker for infection discrimination. Of note, transcriptome-microarray and RNA-seq methods need sophisticated techniques and expertise interpretation, hampering the universal implement of these platforms in low-tier hospitals and under- resourced countries. This study explores transcriptome-based diagnostic biomarker for acute febrile illness , hoping to achieve rapid, accurate and cost-effective distinction between bacterial and viral infection.

Conditions

  • Acute Febrile Illness

Interventions

OTHER

Infection

Pathogens such as bacteria and viruses invade the human body, grow, and proliferation, triggering an immune response.

Sponsors & Collaborators

  • Qilu Hospital of Shandong University

    lead OTHER

Principal Investigators

  • Gang Wang · Qilu Hospital of Shandong University

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2024-12-31
Completion
2025-08-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06552975 on ClinicalTrials.gov