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Anorectal Manometery in Pediatric Chronic Refractory Constipation

NCT06543979 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-10-09

No results posted yet for this study

Summary

Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many institutions. In high resolution anorectal manometery we are able to gain information whether the symptoms are related to sphincter dysfunction, impaired sensation, or pelvic floor dyssynergia

Conditions

  • Chronic Constipation

Interventions

DRUG

lubiprostone , single arm

laxative

PROCEDURE

biofeed back sessions

Biofeedback for participants with dyssynergic defecation and participants with reduced rectal sensations

PROCEDURE

botox injection

Botulinum toxin injection for participants suffering from elevated anal canal pressure

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • asmaa abdelnaby mohamed soliman, master · assistant lecturer

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
4 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-07
Primary Completion
2025-09-01
Completion
2025-10-01
FDA Drug
Yes

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06543979 on ClinicalTrials.gov