MedTrace Logo

Harm Reduction for Smokers With Mental Illness

NCT06543407 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 250

Last updated 2026-01-15

No results posted yet for this study

Summary

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT

Conditions

  • Tobacco Dependence

Interventions

BEHAVIORAL

SWITCH IT

Behavioral support for switching, 7-10 sessions with SWITCH IT coach delivered during the first 8 weeks of the study. SWITCH IT participants will also have the opportunity to receive supported "field trips" to explore e-cigarette options based on availability, cost, and preferences during week 4 and week 6.

OTHER

E-cig Provision Only

Provision of e-cigarettes (NJOY) based on combusible use for the first 8 weeks of the study.

Sponsors & Collaborators

  • Dartmouth College

    collaborator OTHER

  • Fordham University

    collaborator OTHER

  • Seven Counties Services

    collaborator UNKNOWN

  • Western Michigan University School of Medicine

    collaborator OTHER

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Dartmouth-Hitchcock Medical Center

    lead OTHER

Principal Investigators

  • Sarah I. Pratt, PhD · Dartmouth Health

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-01
Primary Completion
2027-12-31
Completion
2028-03-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06543407 on ClinicalTrials.gov