Dynamic Pattern of Etiology, Immunoinflammatory Factors and Their Association With Prognosis of Severe Pneumonia
NCT06538441 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 600
Last updated 2024-08-07
Summary
The goal of this longitudinal observational study is to investigate the pathogen spectrum composition of severe pneumonia (SP) in different disease stages and to study the changes of immune inflammatory factors in patients with SP in different course of disease during and after the COVID-19 pandemic. The main questions it aims to answer is:
What is the pathogenic profile of SP patient admitted in intensive care unit (ICU) during and after COVID-19 pandemic? What is the dynamic pattern of etiology and immunoinflammatory factors of SP progression during the period in ICU? Are those indexes mentioned above associated with the prognosis of SP?
Conditions
- Severe Pneumonia
Sponsors & Collaborators
-
First Affiliated Hospital of Chongqing Medical University
collaborator OTHER -
Shanghai General Hospital, China
lead OTHER
Principal Investigators
-
Mei Kang, MPH · Clinical Research Center, Shanghai General Hospital
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-01
- Primary Completion
- 2025-07-30
- Completion
- 2025-12-30
Countries
- China
Study Locations
More Related Trials
-
Chinese Hospital Acquired Pneumonia Collaboration Network: Epidemiology, Diagnosis and Treatment
NCT06028217 ·Status: NOT_YET_RECRUITING
-
Impact of Severe Acute Respiratory Syndrome (SARS-CoV-2/COVID-19) Related Pneumonia on Lung Function and Structure.
NCT04916834 ·Status: UNKNOWN
-
A Study on the Prospective Cohort Library of COVID-19 in Southeran
NCT04342702 ·Status: UNKNOWN
-
Early Identification and Severity Prediction of Acute Respiratory Infectious Disease
NCT04955756 ·Status: UNKNOWN ·Phase: NA
-
Rapid Diagnosis of Severe Respiratory Tract Infectious Diseases and Screening of Biomarkers for Stratified Diagnosis
NCT06533514 ·Status: NOT_YET_RECRUITING
-
Superinfection and Hyperinflammatory Phenotype in COVID-19 (Coronavirus Disease 2019) Pneumonia Patients
NCT04867161 ·Status: UNKNOWN
-
Effects of Neutrophil Extracellular Traps and Damage-associated Molecular Pattern Molecules on Long Term Use of Macrolides in Adults With Chronic Respiratory Disease
NCT05575726 ·Status: UNKNOWN
-
The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network
NCT06896019 ·Status: ACTIVE_NOT_RECRUITING
-
Metagenomic Study in Parapneumonic Effusion
NCT05394220 ·Status: RECRUITING
-
Monitoring of Antimicrobial Resistance Based on Metagenomics Analyses in Pneumonia Patients
NCT06566898 ·Status: RECRUITING
-
A Validation Study on a Prognostic Prediction Model for Respiratory Tract Infections
NCT07109310 ·Status: NOT_YET_RECRUITING
-
Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration
NCT06288074 ·Status: RECRUITING
-
Investigating the Impact of Sepsis Phenotypes on Antibiotic Treatment in Patients With Severe Pneumonia and Sepsis
NCT06977165 ·Status: NOT_YET_RECRUITING
-
Microecology and Host Immunity in Patients With Severe COVID-19 Infection
NCT05670275 ·Status: UNKNOWN
-
Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study
NCT05612893 ·Status: UNKNOWN
-
Study of Progression of Community Acquired Pneumonia in the Hospital in Patients With More Severe Preexisting Diseases and Immunosuppression
NCT05688774 ·Status: RECRUITING
-
Pulmonary Function in Patients Recovering From COVID19 Infection : a Pilot Study
NCT05074927 ·Status: UNKNOWN ·Phase: NA
-
Definition of Sub-phenotypes of Pneumonia Based on the Respiratory Microbiome Composition to Predict Microbial and Clinical Treatment Failures
NCT06916481 ·Status: RECRUITING
-
Pattern and Outcomes of Chest Diseases
NCT06053528 ·Status: UNKNOWN
-
Clinical Presentations and Outcomes of Patients With Covid-19 Pneumonia
NCT05092555 ·Status: UNKNOWN
-
Bacterial and Fungal Microbiota of Patients With Severe Viral Pneumonia With COVID-19
NCT04359706 ·Status: COMPLETED
-
Second-generation Sequencing Guides the Treatment of Severe Pneumonia
NCT03884881 ·Status: UNKNOWN ·Phase: NA
-
Accurate Classification System for Patients With COVID-19 Pneumonitis
NCT04302688 ·Status: COMPLETED
-
COVID-19 Infection in Patients With Chronic Pulmonary Diseases.
NCT05087199 ·Status: UNKNOWN
-
Immunological Profiling of Patients With COVID-19 in Respiratory Distress
NCT04351711 ·Status: COMPLETED