A Double Blind, Randomized, Cross-over Study Examining the Suppression of the Photoparoxysmal EEG Response With NPT 2042
NCT06525649 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2025-07-16
Summary
A double-blind, placebo-controlled, crossover trial to investigate the PPR of approximately 5 subjects with a known stable PPR on EEG, using 2 doses of NPT 2042 compared to placebo.
Conditions
- Photosensitive Epilepsy
- Epilepsy
Interventions
- DRUG
-
NPT 2042
NPT 2042 is a new drug being developed as an anti-seizure treatment.
Sponsors & Collaborators
-
The Epilepsy Study Consortium
collaborator OTHER -
NeuroPro Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-21
- Primary Completion
- 2025-06-26
- Completion
- 2025-06-26
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome
NCT00200941 ·Status: COMPLETED ·Phase: PHASE4
-
Photosensitivity Proof of Concept Trial
NCT00894010 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy
NCT00784212 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of YKP3089 in Patients With Photosensitive Epilepsy
NCT00616148 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GWP42006 in People With Focal Seizures - Part B
NCT02365610 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures.
NCT00425282 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs
NCT00866775 ·Status: COMPLETED ·Phase: PHASE3
-
An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy
NCT00210652 ·Status: COMPLETED ·Phase: PHASE2
-
An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy
NCT00210522 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Epilepsy.
NCT00236847 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures
NCT00236860 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GWP42006 in People With Focal Seizures - Part A
NCT02369471 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Valproic Acid Concentration on Photic Response
NCT00609245 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of 333369 in the Treatment of Partial Epilepsy
NCT00228969 ·Status: COMPLETED ·Phase: PHASE2
-
A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic Seizures
NCT01393743 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures
NCT05159908 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
NCT00699972 ·Status: COMPLETED ·Phase: PHASE3
-
A Study To Evaluate The Effect Of Topiramate On Clinical And Electrophysiological Parameters In Subjects With Diabetic Peripheral Polyneuropathy
NCT00231673 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures.
NCT00236691 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.
NCT00740623 ·Status: COMPLETED ·Phase: PHASE3
-
A Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset Seizures
NCT01618695 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Tolerability of GWP42006 in Healthy Subjects
NCT01918735 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures.
NCT00236873 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome
NCT02834793 ·Status: TERMINATED ·Phase: PHASE3
-
To Evaluate The Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
NCT00699582 ·Status: COMPLETED ·Phase: PHASE3