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tDCS in People With Subthreshold Depression

NCT06517121 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 204

Last updated 2026-02-02

No results posted yet for this study

Summary

This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.

Conditions

  • Subthreshold Depression

Interventions

DEVICE

Personalized Experimental Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity over personalized brain regions based on the particular neural correlates of socio-affective processing.

DEVICE

Sham Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants assigned to the sham control group will only receive 30 seconds of active stimulation.

DEVICE

Conventional Experimental Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity with anode placed over F3.

Sponsors & Collaborators

  • The University of Hong Kong

    collaborator OTHER

  • Chinese University of Hong Kong

    collaborator OTHER

  • Hong Kong Baptist University

    collaborator OTHER

  • Education University of Hong Kong

    lead OTHER

Principal Investigators

  • Nichol ML Wong, PhD · Education University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-16
Primary Completion
2027-01-31
Completion
2027-01-31

Countries

  • Hong Kong

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06517121 on ClinicalTrials.gov