MedTrace Logo

The Role of Breastmilk and Serum Exosomes in Neonatal Jaundice Due to ABO Incompatibility

NCT06502847 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 338

Last updated 2025-07-18

No results posted yet for this study

Summary

Neonatal jaundice is a major global health issue that can lead to serious complications and even death if not promptly treated. ABO incompatibility is a common cause of pathological neonatal jaundice, but there are currently no specific tests to predict its severity or progression. This project aims to study the role of exosomes in the diagnosis and treatment of newborn jaundice, focusing on their impact on infants with ABO incompatibility. The study will take place at a reference neonatal intensive care unit, involving 45 infants. Serum and breast milk samples will be collected and analyzed to determine any relationships and possible correlations.

Conditions

  • Neonatal Jaundice From Other Specified Causes
  • ABO Incompatibility
  • ABO Hemolytic Disease

Interventions

OTHER

Exosome profile study

Neonatal serum and maternal exosome profiles will be studied in all groups.

Sponsors & Collaborators

  • Kanuni Sultan Suleyman Training and Research Hospital

    lead OTHER

Eligibility

Max Age
28 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2023-06-01
Completion
2023-06-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06502847 on ClinicalTrials.gov