MedTrace Logo

Strokectomy in Malignant Cerebral Media Infarction

NCT06489470 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2024-07-08

No results posted yet for this study

Summary

Decompressive hemicraniectomy (DC) is the standard procedure and life saving measure in case of malignant middle cerebral artery (MCA) infarction. However, there have been several studies reporting the neuroinflammatory cascade based on the necrotic tissue as one of the leading cause for the secondary brain damage, wherefore, strokectomy with resection of necrotic tissue has been proposed in some case series as an alternative surgical option. Thus, the aim of this study is to perform a pilot study by including patients with malignant MCA infarction and to check the feasibility of this specific surgical treatment.

Conditions

  • Stroke, Ischemic

Interventions

PROCEDURE

Strokectomy/Necrosectomy

After obtaining CT-/MRT-perfusion, the infarcted area (e.g. infarct core) of malignant MCA-infarction is localized. By using the neuronavigation, surgical resection of necrotic tissue is performed in a non-eloquent area until the space occupying effect is released. At the end of the surgery, the bone flap is reinserted and fixated.

Sponsors & Collaborators

  • University of Rostock

    lead OTHER

Principal Investigators

  • Sae-Yeon Won, MD · Neurosurgery, University Medical Center Rostock

  • Florian Gessler, MD PhD · Neurosurgery, University Medical Center Rostock

  • Matthias Wittstock, MD · Neurology, University Medical Center Rostock

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-15
Primary Completion
2025-03-31
Completion
2025-06-30

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06489470 on ClinicalTrials.gov