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Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood

NCT06486909 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2026-03-18

No results posted yet for this study

Summary

The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS dependency in patients suffering from an aneurysmal subarachnoid haemorrhage (aSAH). The main questions we aim to answer are:

* Is there an association of glucose levels on VPS dependency in patients requiring extra-ventricular-drain (EVD) placement for aSAH?
* In addition, if there is, what is the influence the course of glucose levels has on VPS dependency?

Glucose levels in CSF and serum will be measured on admission, or in case of CSF, upon EVD placement. Glucose in CSF will then be measured every day until EVD removal together with serum glucose. Follow-up will be conducted in person after 3 and 6 months.

Conditions

Interventions

DIAGNOSTIC_TEST

Cerebrospinal Fluid (CSF) Sample

Samples for glucose in CSF will be taken upon EVD/LD placement until EVD/LD removal (within the first 14 days).

DIAGNOSTIC_TEST

Blood Serum Sample

Samples for glucose in blood serum will be completed every day, for the first 14 days.

Sponsors & Collaborators

  • Kantonsspital Aarau

    collaborator OTHER

  • University Hospital, Basel, Switzerland

    collaborator OTHER

  • Isabel Hostettler

    lead OTHER

Principal Investigators

  • Isabel Hostettler, MD PhD · Cantonal Hospital of St. Gallen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-26
Primary Completion
2027-03-31
Completion
2028-09-30

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06486909 on ClinicalTrials.gov