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A Study of Radiation Therapy After Surgery in People With Oral Tongue Squamous Cell Carcinoma

NCT06485778 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-02-04

No results posted yet for this study

Summary

This study will test whether limiting standard photon intensity modulated radiation therapy (IMRT) to exclude the oral tongue surgical site can decrease the risk of side effects caused by oral radiation. The researchers will also find out if this approach affects the rate of disease coming back after treatment (recurrence), and will measure participants' quality of life by having them complete questionnaires.

Conditions

  • Oral Tongue Squamous Cell Carcinoma

Interventions

RADIATION

Photon intensity modulated radiation therapy (IMRT)

Patients will receive bilateral cervical nodal irradiation with the primary post operative site excluded (30 fractions).

OTHER

Life questionnaire's

EORTC QLQ C30/HN 35 and MDADI

Sponsors & Collaborators

Principal Investigators

  • Sean McBride, MD, PhD · Memorial Sloan Kettering Cancer Center

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-27
Primary Completion
2026-06-30
Completion
2026-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06485778 on ClinicalTrials.gov