Trial Outcomes & Findings for Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) Lens (NCT NCT06479148)

NCT ID: NCT06479148

Last Updated: 2026-05-26

Results Overview

Photopic binocular distance corrected intermediate visual acuity (DCIVA) at 66 cm at post-operative visit 3

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

27 participants

Primary outcome timeframe

Assessed from Day 90 to Day 150

Results posted on

2026-05-26

Participant Flow

Participant milestones

Participant milestones
Measure
enVista® Aspire ™
enVista® Aspire™: Eyes will receive enVista® Aspire™ lenses
An IOL With a Slightly Extended Depth of Focus
An IOL with a slightly extended depth of focus: Eyes will receive lenses with a slightly extended depth of focus
enVista® Monofocal IOL (MX60E)
Other MX60E: Eyes will receive MX60E lenses
Overall Study
STARTED
11
10
6
Overall Study
COMPLETED
0
0
0
Overall Study
NOT COMPLETED
11
10
6

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) Lens

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
An IOL With a Slightly Extended Depth of Focus
n=10 Participants
An IOL with a slightly extended depth of focus: Eyes will receive lenses with a slightly extended depth of focus
enVista® Monofocal IOL (MX60E)
n=6 Participants
Other MX60E: Eyes will receive MX60E lenses
Total
n=27 Participants
Total of all reporting groups
enVista® Aspire ™
n=11 Participants
enVista® Aspire™: Eyes will receive enVista® Aspire™ lenses
Age, Categorical
<=18 years
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Age, Categorical
Between 18 and 65 years
1 Participants
n=32 Participants
1 Participants
n=64 Participants
4 Participants
n=50 Participants
2 Participants
n=20 Participants
Age, Categorical
>=65 years
9 Participants
n=32 Participants
5 Participants
n=64 Participants
23 Participants
n=50 Participants
9 Participants
n=20 Participants
Sex: Female, Male
Female
8 Participants
n=32 Participants
4 Participants
n=64 Participants
19 Participants
n=50 Participants
7 Participants
n=20 Participants
Sex: Female, Male
Male
2 Participants
n=32 Participants
2 Participants
n=64 Participants
8 Participants
n=50 Participants
4 Participants
n=20 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Race (NIH/OMB)
Asian
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Race (NIH/OMB)
White
10 Participants
n=32 Participants
6 Participants
n=64 Participants
27 Participants
n=50 Participants
11 Participants
n=20 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=32 Participants
0 Participants
n=64 Participants
0 Participants
n=50 Participants
0 Participants
n=20 Participants
Region of Enrollment
Honduras
10 participants
n=32 Participants
6 participants
n=64 Participants
27 participants
n=50 Participants
11 participants
n=20 Participants

PRIMARY outcome

Timeframe: Assessed from Day 90 to Day 150

Population: Due to early termination, this outcome was not measured, as none of the subjects underwent a visit 3.

Photopic binocular distance corrected intermediate visual acuity (DCIVA) at 66 cm at post-operative visit 3

Outcome measures

Outcome data not reported

Adverse Events

enVista® Aspire ™

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

An IOL With a Slightly Extended Depth of Focus

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

enVista® Monofocal IOL (MX60E)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Natasa Orlic-Pleyer MD

Bausch & Lomb

Phone: +49 30 330 93 - 318

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place