Trajectories and Experiences of People With Multimorbidity in Spain (LOXO-MULTIPAP) Project: a Mixed Methods Study

Summary

The overall objective of the study is to analyze the evolution of multimorbidity, its most relevant patterns and trajectories in the Spanish National Health System population, from 2012 to 2022, and to analyze the factors that determine it, as well as the experience of professionals and patients in navigating the health system and in shared decision making.

Multimorbidity trajectories can help identify homogeneous groups of individuals with similar needs and prognoses, and help practitioners and health systems to personalize clinical interventions and preventive strategies. Capturing this dynamism is the only way to better understand the natural history of multimorbidity and shed light on hitherto unexplained findings.

Conditions

• Multimorbidity

Interventions

OTHER

Retrospective and prospective cohort

* Retrospective study: Population-based retrospective cohort study with RWD. Patients ≥60 years old with 2 or more chronic diseases diagnosed before 01/01/2012, users of the public health system of the participating Autonomous Communities, will be included. Those who have had no contact with primary care defined as contact in a medical or nursing consultation in the previous two years (2010-2012) will be excluded. * Prospective longitudinal observational open cohort study developed in the context of the MULTIPAP and LOXO studies.Patients over 65 years of age with multimorbidity (3 or more chronic pathologies) and polypharmacy (5 or more drugs taken during at least the last 3 months before inclusion in the study) under follow-up from primary care in Madrid, Aragon and Andalusia.

OTHER

Focus group, semi-structured interviews and Photovoice

The participants will be people with multimorbidity over 60 years of age recruited from Primary Care centers in Spain. A theoretical sampling will be carried out. Data will be collected through video and audio recordings from a total of 16 focus groups and 20 interviews in 7 regions, and will finally be transcribed for a triangulated thematic analysis. Two groups will be carried out with participation-action research methodology - Photovoice.

OTHER

Systematic review

No patient recruitment required

Sponsors & Collaborators

• PI. Bernardino Oliva. Instituto Investigación Sanitaria Illes Balears

  collaborator UNKNOWN

• PI. Concepción Violan. Fundacion Jordi Gol i Gurina

  collaborator UNKNOWN

• PI Antonio Gimeno. Instituto de Investigación Sanitaria Aragón.

  collaborator UNKNOWN

• PI. Rafael Rotaeche. Instituto Investigación Bioguipuzcoa. Osakidetza

  collaborator UNKNOWN

• PI. Francisca Leiva. Instituto de Investigacion Biomedica de Malaga.

  collaborator UNKNOWN

• CI. Julian Librero. Navarra Biomed. Servicio Navarro de Salud

  collaborator UNKNOWN

• Fundación Investigacion en Innovacion Biomédica en Atención Primaria FIIBAP

  collaborator UNKNOWN

• Instituto de Investigación Sanitaria Gregorio Marañón

  collaborator OTHER

• Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina

  collaborator OTHER

• Gerencia de Atención Primaria, Madrid

  lead OTHER_GOV

Principal Investigators

• Isabel del Cura González, PhD,MD · Gerencia Asistencial de Atención Primaria

Eligibility

Min Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-06-30

Primary Completion

2025-07-01

Completion

2027-07-01

Countries

• Spain

Study Locations