Combined Screening for Gastrointestinal Tumors

Summary

All participants are required to complete a questionnaire, a Helicobacter pylori (H. pylori) test, and a fecal immunochemical test (FIT). The questionnaire covers nine aspects: basic information of the participants, symptoms and previous examinations, medical history and surgical history, medication history, smoking history, alcohol consumption history, dietary habits, physical exercise, and family history. After quality control, the data is entered by staff into the Zhejiang Province Cancer Screening Information Platform. Risk assessments are performed based on the data collected and high-risk individuals are recommended for clinical screening. Additionally, tongue image, stool, urine, blood, tongue coating, saliva, gastric juice, and fresh tissue (gastric mucosa tissue and/or intestinal polyp tissue) samples are collected from all participants undergoing clinical screening.

Participants are required to complete at least one passive follow-up annually. Active follow-ups are conducted for those with positive screening results to ensure timely completion of endoscopic examinations. For those who have not undergone endoscopic examinations despite positive screening results, health education is provided, and they are mobilized at least four times within one month to complete endoscopic examinations. For participants diagnosed and treated for precancerous lesions and tumors, diagnostic and treatment data must be collected, and they are encouraged to follow up as per medical advice. Both active and passive follow-up results must be recorded in the screening follow-up information record form and reported to the Zhejiang Province Cancer Screening Information Platform.

This is a government collaboration project. All subjects will also be followed by record linkage to Cancer Register and Population Register.

Conditions

• Gastrointestinal Tumors

Interventions

DIAGNOSTIC_TEST

questionnaire, Helicobacter pylori (H. pylori) test, fecal immunochemical test (FIT)

The questionnaire covers nine aspects: basic information of the participants, symptoms and previous examinations, medical history and surgical history, medication history, smoking history, alcohol consumption history, dietary habits, physical exercise, and family history.

Sponsors & Collaborators

• Fenghua District People's Hospital, Ningbo City

  collaborator UNKNOWN

• Fenghua District Traditional Chinese Medicine Hospital, Ningbo City

  collaborator UNKNOWN

• Xikou Hospital in Fenghua District, Ningbo City

  collaborator UNKNOWN

• Yongkang Traditional Chinese Medicine Hospital

  collaborator UNKNOWN

• Hangzhou Medical College

  collaborator OTHER

• Zhejiang Cancer Hospital

  lead OTHER

Eligibility

Min Age

40 Years

Max Age

74 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-03-01

Primary Completion

2027-12-31

Completion

2028-12-31

Countries

• China

Study Locations