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Pregnancy Outcomes Following Myomectomy

NCT06474065 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2026-01-23

No results posted yet for this study

Summary

The most prevalent genital pathology, uterine fibroids have a detrimental impact on the health of women. Fibroid symptoms are typically more impactful on females and frequently require uterine excision. Although contentious in terms of how it affects pregnancy outcomes, hysteroscopic, laparoscopic, or laparotomic myomectomy has always been a necessary and suitable procedure for the patient's health. Numerous studies have been conducted on the topic, but no clear findings have been reached.

The goal of this observational study is to investigate the pregnancy outcomes after hysteroscopic, laparoscopic, laparotomic myomectomies in female patients affected by fibroids. The main questions it aims to answer are:

To investigate pregnancy outcomes in relation to surgical approach used for myomectomy.

To investigate whether pregnancy outcome is different in relation to time when myomectomy was performed: on a pregnant uterus or on a non-gravid uterus.

If there is a comparison group: Researchers will compare a group of patients unsubmitted to surgery, to see the difference with the operated patients.

Participants will follow up, to evaluate the possible pregnancy complications, the intraoperative complications and other perinatal and post-operative complications.

Conditions

  • Pregnancy Complications
  • Uterine Fibroid
  • Reproductive Issues
  • Reproductive Sterility

Interventions

PROCEDURE

Myomectomy

Patients submitted to operation of fibroids removal

Sponsors & Collaborators

  • Centro di Ricerca Clinica Salentino

    lead NETWORK

Principal Investigators

  • Andrea Tinelli, MD · Centro di Ricerca Clinica Salentino

Eligibility

Min Age
25 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-28
Primary Completion
2025-10-30
Completion
2025-12-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06474065 on ClinicalTrials.gov