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Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies

NCT06471387 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2024-06-25

No results posted yet for this study

Summary

This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets. The project will involve drug repurposing using Mendelian Randomization, a smoking cessation intervention, and the analysis of methylation status in participants undergoing nicotine withdrawal.

Conditions

  • Smoking Cessation
  • Smoking Cessation Intervention
  • Nicotine Addiction
  • Epigenetics
  • Molecular Biology
  • Genetic Epidemiology

Interventions

BEHAVIORAL

Flexiquit Smoking Cessation Intervention

Participants will enter a 6-week (once weekly) self-delivered computerized intervention program called Flexiquit. Developed and validated by Clinical Psychologists of the Department of Psychology at the University of Cyprus, Flexiquit is an avatar-led app designed to support smoking cessation. It aims to assist with abstinence and monitor participants' progress through personalized modules and assessments.

Sponsors & Collaborators

  • University of Cyprus

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-01
Primary Completion
2025-10-31
Completion
2025-10-31

Countries

  • Cyprus

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06471387 on ClinicalTrials.gov