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Cerebrovascular Disease: Quality of Life (CODE: QoL)

NCT06443268 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 680

Last updated 2024-06-05

No results posted yet for this study

Summary

The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.

The main question is:

• to discover the factors associated with quality of life and stress in patient-caregiver dyads.

Participants will be asked to fill out questionnaires and agree to provide a hair sample (in order to measure stress hormones in hair) and consent to use of their routine clinical and laboratory data.

Researchers will compare a group of participants without stroke to establish a comparable baseline.

Conditions

  • Quality of Life
  • Stroke, Acute
  • Sexual Behavior
  • Stress
  • Cortisol Excess
  • Incontinence, Urinary
  • Caregiver Burden
  • Transient Ischemic Attack
  • Intracerebral Hemorrhage
  • Cerebrovascular Disorders

Interventions

DIAGNOSTIC_TEST

questionnaire, hair samples, blood samples, clinical exam

The following parameters will be sequentially assessed in caregivers and patients (baseline, at 3 months and at 12 months): 1) quality of life / functioning will be determined through questionnaires (SF-36, EQ-5DL, ECOG (Eastern Cooperative Oncology Group) / Karnofsky, Barthel Index, ICIQ) 2) stress levels \& anxiety levels, caregiver burden will be assessed by the following questionnaires: Distress Thermometer, SBQ-G, GAD-7, PHQ-9, PSS-10, ZBI, PAC. Cortisol will be measured in hair to indicate stress within the past 3 months \[18\]. Fasting glucose, lipid profiles and HbA1c along with blood count, sodium, potassium, creatinine, TSH (thyroid-stimulating hormone) will be measured in routine blood samples from patients at the time of clinical checkups. Blood pressure, pulse and BMI will be determined during clinical visit in patients and additionally in caregivers.

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Susanne Wegener, MD · University of Zurich

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-27
Primary Completion
2028-04-30
Completion
2028-06-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06443268 on ClinicalTrials.gov