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EKLF Gene Expression in β-thalassemia

NCT06440603 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2024-06-04

No results posted yet for this study

Summary

1. Studying the effect of expression pattern of EKLF gene in β-thalassemic patients.
2. Detecting the correlation between the gene expression of EKLF and the clinical phenotype of β-thalassemic patients.

Conditions

  • β-thalassemia

Interventions

DIAGNOSTIC_TEST

PCR

Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) for detection of EKLF: * The method of total RNA extraction: TRIZOL and TRIZOL LS. * The purity and concentration of the RNA will be measured using Nano Drop 2000 instument. * cDNA will be done with primers using thr Goscript Reverse Transcription System

Sponsors & Collaborators

  • Rofaida Hassan Ahmed

    lead OTHER

Principal Investigators

  • Eman Naser Eldin · Assiut University

  • Sherif Helmy · Assiut University

  • Reem Elagoz · Assiut University

Eligibility

Min Age
5 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-01
Primary Completion
2026-07-01
Completion
2027-07-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06440603 on ClinicalTrials.gov