Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma
NCT06430424 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2025-07-30
Summary
Glioblastomas are the most frequent and aggressive malignant tumors of the CNS in adults, with almost systematic relapse despite treatment with surgery followed by radio-chemotherapy (STUPP protocol). The aim of this study is to better characterize transcriptomic, proteomic and metabolic changes in relapsed glioblastoma compared to the initial tumor, in order to identify new prognostic markers and potential new therapeutic targets.
Conditions
- Relapsed Cancer
- Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Interventions
- BIOLOGICAL
-
Relapsed glioblastoma
Paired tumor samples diagnosis/relapse
Sponsors & Collaborators
-
University Hospital, Bordeaux
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-04-05
- Primary Completion
- 2025-07-31
- Completion
- 2026-04-30
Countries
- France
Study Locations
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