Study of Olverembatinib (HQP1351) in Patients With CP-CML
NCT06423911 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 285
Last updated 2025-06-03
Summary
A Global Multicenter, Open Label, Randomized, Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients with Chronic Phase Chronic Myeloid Leukemia (POLARIS-2)
Conditions
- Chronic Myeloid Leukemia
- CML
- CML, Chronic Phase
Interventions
- DRUG
-
olverembatinib
olverembatinib QOD
- DRUG
-
Bosutinib
Bosutnib QD
Sponsors & Collaborators
-
Ascentage Pharma Group Inc.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-05
- Primary Completion
- 2025-12-31
- Completion
- 2026-02-28
- FDA Drug
- Yes
Countries
- United States
Study Locations
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