Study of Olverembatinib (HQP1351) in Patients With CP-CML

NCT06423911 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 285

Last updated 2025-06-03

No results posted yet for this study

Summary

A Global Multicenter, Open Label, Randomized, Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients with Chronic Phase Chronic Myeloid Leukemia (POLARIS-2)

Conditions

  • Chronic Myeloid Leukemia
  • CML
  • CML, Chronic Phase

Interventions

DRUG

olverembatinib

olverembatinib QOD

DRUG

Bosutinib

Bosutnib QD

Sponsors & Collaborators

  • Ascentage Pharma Group Inc.

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-05
Primary Completion
2025-12-31
Completion
2026-02-28
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06423911 on ClinicalTrials.gov