Study on the Pathogenesis of Retinal Vascular Diseases Based on Body Fluid Metabolomics
NCT06408571 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 3900
Last updated 2024-05-10
Summary
Through the analysis of metabolites in body fluids (intraocular fluid, plasma) of patients with retinal vascular diseases (retinal vein occlusion, diabetic retinopathy), the possible pathogenesis of retinal vein occlusion was explored.
Conditions
- Metabolomics; Retinopathy; Etiology
Interventions
- OTHER
-
etiology
As an important part of systems biology, metabolomics mainly detects various metabolites in the sample. Different from nucleic acids, proteins and other biological macromolecules, the relative molecular weight of these metabolites is small, generally within 1000Da, such as amino acids, carboxylic acids, carbohydrates, alcohols, amines, lipids and other special substances. Through qualitative and quantitative analysis of all endogenous low molecular weight metabolites before and after pathophysiology or gene modification stimulation, metabolomics reveals the essential characteristics of life activities and metabolism of the body, and provides guidance for exploring the pathogenesis, early diagnosis, treatment and prognosis of diseases.
Sponsors & Collaborators
-
Zhongnan Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-09-07
- Primary Completion
- 2024-10-30
- Completion
- 2024-12-30
Countries
- China
Study Locations
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