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Effect of Local Estriol Treatment Before Vaginal Repair Surgery

NCT06391372 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2025-02-05

No results posted yet for this study

Summary

The aim of the study is to evaluate the effects of local estriol treatment applied before vaginal repair surgery on steroid receptors, inflammatory cell response, vascular, connective and nervous tissues in the vagina, and its effects on early postoperative period pelvic floor functions, satisfaction with the surgery and vaginal health.

Conditions

  • Pelvic Organ Prolapse
  • Pelvic Floor Disorders
  • Menopause
  • Vaginal Atrophy

Interventions

DRUG

estriol cream

1 g intravaginal estriol via applicator twice a week before going to bed for 4 weeks

Sponsors & Collaborators

  • Hatice Tukenmez Kurnaz

    lead OTHER

Principal Investigators

  • Fulya Dokmeci · Ankara University Faculty of Medicine, Department of Gynecology and Obstetrics

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-01
Primary Completion
2025-03-31
Completion
2025-03-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06391372 on ClinicalTrials.gov