Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients

Summary

Using mechanical ventilation for more than 18 hours can affect respiratory muscle and postural muscle control, making it difficult to wean off the ventilator and reducing mobility. The aim of this study is to:

1. Compare the effects of respiratory muscle strength training and early mobilization on dynamic lung compliance and maximum inspiratory pressure before and after a 7-day training period.
2. Compare the success rate of weaning and the duration of weaning between the respiratory muscle strength training and the early mobilization program.

Conditions

• Ventilator Dependent

Interventions

OTHER

Inspiratory muscle training (IMT) group

The IMT group receives inspiratory muscle training of 50%MIP, 6 breaths/set 10 sets/day for 7 days combined with conventional chest physiotherapy including; percussion, vibration, postural draining, positioning, and passive range of motion.

OTHER

Early mobilization (EM) group

The ER group received active exercise in sitting, standing, and marching 30 minutes/day for 7 days with conventional chest physical therapy

Sponsors & Collaborators

• Prince of Songkla University

  lead OTHER

Principal Investigators

• Saikaew Chuachan · Department of Physical Therapy, Faculty of Medicine, PSU

• Natcha Kimthiaw, Bsc.PT · Department of Physical Therapy, Faculty of Medicine, PSU

• Luksamee Kaewchano, Bsc.PT · Department of Physical Therapy, Faculty of Medicine, PSU

• Ittiphon Pannarai, Bsc.PT · Department of Physical Therapy, Faculty of Medicine, PSU

• Jatuporn Jaturawanit, Bsc.PT · Physical Therapy unit, Songklanakarind Hospital

• Jitsupa Kittarakul, Bsc.PT · Physical Therapy unit, Songklanakarind Hospital

• Boonmas Chansirimongkol, B.N.S. · Medical Respiratory Care Unit, Prince of Songklanakarind Hospital

• Kwankamol Kalsri, B.N.S · Medical Respiratory Care Unit, Prince of Songklanakarind Hospital

• Assoc.Prof.Siwasak Juthong, MD · Division of Respiratory and Respiratory Critical Care Medicine, Department of Internal Medicine, PSU

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-05-06

Primary Completion

2026-02-28

Completion

2026-03-31

Countries

• Thailand

Study Locations