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WoW - Single- vs Two-staged Excisions of Thin Melanoma

NCT06363591 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2486

Last updated 2025-03-05

No results posted yet for this study

Summary

The overall aim of this national, multicenter, prospective, randomized, and controlled study is to enhance the management of patients with thin melanoma (≤1 mm Breslow thickness). The investigators hypothesize that wide local excisions (WLEs) following complete excision of thin melanoma do not affect the risk of recurrence, defined as the occurrence of local, regional, distant disease, or melanoma-specific death during a 5- to 10-year follow-up period.

Conditions

Interventions

PROCEDURE

Surgery

Wise or wide excision

OTHER

No Surgery

No wide local excision

Sponsors & Collaborators

  • Region Stockholm

    collaborator OTHER_GOV

  • Region Skane

    collaborator OTHER

  • Region Västerbotten

    collaborator OTHER_GOV

  • Region Örebro County

    collaborator OTHER

  • Blekinge County Council Hospital

    collaborator OTHER

  • Region Östergötland

    collaborator OTHER

  • Dalarna County Council, Sweden

    collaborator OTHER

  • Vastra Gotaland Region

    lead OTHER_GOV

Principal Investigators

  • John Paoli, Professor · Dept. of Dermatology and Venereology, Sahlgrenska Academy, University of Gothenburg, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-22
Primary Completion
2034-12-31
Completion
2039-12-31

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06363591 on ClinicalTrials.gov