A Phase II Study of SSGJ-707 Monotherapy in First-line PD-L1 Positive Advanced NSCLC Patients
NCT06361927 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2024-05-16
Summary
This study includes two cohorts, cohort A is for non-squamous NSCLC and cohort B is for squamous NSCLC.
Conditions
Interventions
- DRUG
-
SSGJ-707
bispecific antibody
Sponsors & Collaborators
-
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Lin Wu, MD, Ph.D · The Hunan Cancer Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-05-15
- Primary Completion
- 2025-06-30
- Completion
- 2025-07-31
Countries
- China
Study Locations
More Related Trials
-
Surufatinib Combined With Toripalimab and Chemotherapy in the Treatment of Non-Small Cell Lung Cancer
NCT05003037 ·Status: UNKNOWN ·Phase: PHASE2
-
Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations
NCT07117890 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Toripalimab for Non-squamous NSCLC With EGFR Mutation
NCT05962021 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of SCT200 in Patients With Advanced Squamous Non-small Cell Lung Cancer
NCT03808701 ·Status: UNKNOWN ·Phase: PHASE1
-
Real-world Study of Sunvozertinib Treatment in Advanced EGFR-Mutant NSCLC After EGFR-TKI Treatment Failure
NCT06786208 ·Status: NOT_YET_RECRUITING
-
Gefitinib in Combination With Anlotinib or Placebo in Previously Untreated EGFR-mutant NSCLC
NCT04028778 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer
NCT05297890 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
SH-1028 Tablets Versus Placebo as Adjuvant Therapy in Resected Stage II-IIIB NSCLC With Sensitizing EGFR Mutations
NCT06080776 ·Status: RECRUITING ·Phase: PHASE3
-
Third-generation EGFR-TKI Plus Anlotinib as Maintenance for NSCLC With Small Cell Transformation After EGFR-TKI Resistance
NCT06634667 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RW
NCT06355609 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of SH-1028 in Locally Advanced or Metastatic NSCLC
NCT03823807 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Evaluate Safety and Efficacy of HS-10296 as First-Line Treatment in Patients
NCT03849768 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases
NCT04603807 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
S-1 Plus Gefitinib Versus Gefitinib Monotherapy in Patients With EGFR-sensitive Mutation Advanced Non-squamous NSCLC
NCT03457337 ·Status: UNKNOWN ·Phase: PHASE2
-
The Purpose of Study is to Evaluate the Safety, Pharmacokinetics and Anti-tumor Effects of CKD-702 in Patients With Advanced or Metastatic Non-small Cell Lung Cancer Who Failed to Standard Therapy
NCT04667975 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase 1/2 Study of HS-10376 in Patients With Non-Small Cell Lung Cancer
NCT05435274 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC
NCT06690671 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Sequential Use of Low-dose Sunitinib With Chemotherapy in Advanced NSCLC After Failure of Conventional Regimen
NCT01850147 ·Status: UNKNOWN ·Phase: PHASE2
-
Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC
NCT06348927 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Pyrotinib in Patients With HER2 Mutation Advanced Non-Small Cell Lung Cancer
NCT02535507 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Alkotinib in Patients With Advanced Non Small Cell Lung Cancer
NCT03607188 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of ES102 in Combination With Toripalimab in Subjects With Advanced Non-small Cell Lung Cancer
NCT06623136 ·Status: RECRUITING ·Phase: PHASE2
-
High-dose Icotinib Treatment Beyond Progression in EGFR Mutant NSCLC
NCT02960607 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC
NCT05394831 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer
NCT06685718 ·Status: TERMINATED ·Phase: PHASE1