MedTrace Logo

Heart-brain-axis and Psychosocial Stress

NCT06345573 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 64

Last updated 2026-05-07

No results posted yet for this study

Summary

The main study objective is to prospectively determine the influence of sex-related risk factors and psychosocial variables on neuronal stress responses and myocardial perfusion in a population of 64 female and male individuals 50-75 years of age and free of cardiovascular disease.

Conditions

  • Mental Stress
  • Myocardial Ischemia
  • Sex Role
  • Gender

Interventions

BEHAVIORAL

Mental stress

Two consecutive validated mental stress tests, namely 1) the Montreal Imaging Stress Task consisting of two series of 15-minute mental calculation tests, without (Control Mode) and with (Stress Mode) negative feedback, respectively; and 2) the Trier Social Stress Test consisting of a 5-minute mock job interview (Speech Part) followed by a 5-minute mental calculation test (Mental Arithmetic Part).

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Cathérine Gebhard, Professor · University of Zurich

Eligibility

Min Age
50 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-11
Primary Completion
2023-11-20
Completion
2024-11-20

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06345573 on ClinicalTrials.gov