Trial Outcomes & Findings for Intra-articular Platelet-Rich Plasma for Acetabular Labral Tears (NCT NCT06332352)

Patients were recruited from March through December 2024. Patients were clinically diagnosed with a symptomatic acetabular labral tear by a primary care or orthopedic sports medicine physician in a tertiary outpatient, orthopedic clinic setting. Patients who met inclusion criteria were referred to the study and given the option of participation.

This was an open-label study; therefore, no randomization was performed. In some cases, participants had more than one hip enrolled, accounting for the difference between the number of participants (n=28) and the number of units/hips enrolled (n=30).

Unit of analysis: Hips

Some participants had two different hips enrolled in the study, which explains the difference between the number of participants and the number of hips (units) analyzed.

Global patient satisfaction was assessed prospectively at 6 months following the intervention using a numeric rating scale ranging from 0 to 100. Participants were asked to rate their hip, where 0 represented "worst possible" and 100 represented "best possible." The score reflects the participant's overall perception of their injection, including symptom improvement and overall experience.

Description: The International Hip Outcome Tool-12 (iHOT-12) is a validated, patient-reported outcome measure designed to assess symptoms, functional limitations, and quality of life in young, active individuals with hip disorders. Structure: The iHOT-12 consists of 12 items that capture four domains: Symptoms and Functional Limitations Sports and Recreational Activities Job-Related Concerns Social, Emotional, and Lifestyle Concerns Each item is presented as a visual analog scale (VAS). Scoring: Each item is scored from 0 to 100. 0 = severe symptoms/extreme limitations 100 = no symptoms/no limitations The overall score is calculated as the mean of all answered items (range 0-100), with higher scores indicating better hip function and quality of life.

The EQ Visual Analog Scale (EQ VAS) was used to assess participants' self-rated overall health at the primary end-point. Participants rated their health on a scale from 0 to 100, where 0 represents the worst imaginable health and 100 represents the best imaginable health. Higher scores indicate better perceived health status.