Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature
NCT06332131 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 25
Last updated 2026-02-09
Summary
This is an observational study that includes patients with breast cancer or non-small cell lung cancer who will be treated with immune checkpoint inhibitor (ICI) therapy. The investigators will use echocardiograms, blood draws, and PET stress tests to understand how ICI therapy affects the heart and circulatory system.
Conditions
- Coronary Microvascular Dysfunction
- Cardiotoxicity
- Breast Cancer
- Lung Cancer (NSCLC)
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Marielle Scherrer-Crosbie, MD, PhD · University of Pennsylvania
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-15
- Primary Completion
- 2026-07-31
- Completion
- 2026-07-31
Countries
- United States
Study Locations
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