Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer
NCT06314750 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 186
Last updated 2025-08-14
Summary
Neoadjuvant therapy is the standard diagnosis and treatment strategy for locally advanced rectal cancer defined by MRI in order to achieve tumor regression, thus affecting the selection of surgical strategy and circumferential margin, improving the safety of operation and the prognosis of patients. This study focused on the related clinical factors such as tumor regression before and after neoadjuvant therapy, combined with preoperative high-dimensional features such as radiomics, to predict the related factors of tumor regression of locally advanced rectal cancer, and validate it with multicenter. In order to develop an accurate model that can be applied to the real world and stratify the risk of locally advanced rectal cancer patients before treatment.
Conditions
- Locally Advanced Rectal Carcinoma
Sponsors & Collaborators
-
Sixth Affiliated Hospital, Sun Yat-sen University
lead OTHER
Principal Investigators
-
Zerong Cai, MD · Sixth Affiliated Hospital, Sun Yat-sen University
Eligibility
- Min Age
- 20 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-01-01
- Primary Completion
- 2023-09-30
- Completion
- 2025-06-30
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