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The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)

NCT06312605 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2024-03-15

No results posted yet for this study

Summary

The goal of this clinical trial is to determine the role of vitamin C on recurrence of gingival pigment after patients who are healthy and esthetically concerned with it received surgical removal of this pigment. The main question\[s\] it aims to answer are:

* Pigment recurrence after one year.
* Patient satisfaction and histological response of tissues.

Participants will be asked to come on regular follow up visits one group will receive vitamin C injection other will be asked to apply topical vitamin C on a specific regimen.

Researcher will compare the groups who received injectable vitamin C with those who topically applied it to see the effect of each.

Conditions

  • Gingival Pigmentation

Interventions

PROCEDURE

Injectable applied vitamin C

Surgical gingival depigmentation is done for all participants, after then they receive injectable vitamin C

PROCEDURE

Topical applied Vitamin C

Surgical gingival depigmentation is done for all participants, after then they are instructed to apply topical vitamin C

PROCEDURE

Surgical depigmentation only

Surgical gingival depigmentation only without any drug

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Hala K. Abd-El-Gaber, Professor · Professor of Oral Medicine, Oral Diagnosis and Periodontology Faculty of Dentistry - Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-08-01
Primary Completion
2024-08-31
Completion
2024-08-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06312605 on ClinicalTrials.gov