The Effect of Semaglutide on Cardiovascular Markers and Liver Function
NCT06301191 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2024-03-08
Summary
Fifty patients with diabetes mellitus type 2 and non-alcoholic fatty liver disease (NAFLD) will be enrolled in the study.
25 patients will treated with semaglutide and 25 patients with dipeptidyl peptidase 4 (D-PP4) inhibitors.
At baseline, at four and at 12 months will evaluate the endothelial, cardiovascular and liver function.
Conditions
- Diabetes Type 2
Interventions
- DRUG
-
Semaglutide, 1.0 mg/mL
Semaglutide, 1.0 mg/mL
- DRUG
-
Dipeptidyl Peptidase 4 inhibitor
Dipeptidyl Peptidase 4 inhibitor
Sponsors & Collaborators
-
Attikon Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-01
- Primary Completion
- 2023-03-01
- Completion
- 2024-05-01
Countries
- Greece
Study Locations
More Related Trials
-
Semaglutide Treatment On Coronary Progression
NCT03985384 ·Status: COMPLETED ·Phase: PHASE4
-
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes
NCT03914326 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease
NCT06409130 ·Status: COMPLETED ·Phase: PHASE2
-
Combined Active Treatment in Type 2 Diabetes with NASH
NCT04639414 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate Formulations
NCT05766709 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Dulaglutide on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
NCT03590626 ·Status: COMPLETED ·Phase: NA
-
The Effect of Liraglutide Treatment on Postprandial Chylomicron and VLDL Kinetics, Liver Fat and de Novo Lipogenesis
NCT02765399 ·Status: COMPLETED ·Phase: PHASE4
-
A Trial Investigating the Effects of Semaglutide on ß-cell Function in Subjects With Type 2 Diabetes
NCT02212067 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice (SURE GERMANY)
NCT04261933 ·Status: COMPLETED
-
Effect of Liraglutide on Fatty Liver Content and Lipoprotein Metabolism
NCT02721888 ·Status: TERMINATED ·Phase: PHASE4
-
Semaglutide Treatment in Type 1 Diabetes
NCT06909006 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
The Role of Glucagon-Like Peptide-1 Receptor Agonists in Coronary Artery Diseases and Their Potential Mechanisms
NCT07073053 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long-acting GLP-1 Analogue in Healthy Male Subjects and Male Subjects With Type 2 Diabetes
NCT01686945 ·Status: COMPLETED ·Phase: PHASE1
-
Semaglutide as an Adjunct to Dieting in the Treatment of Type 2 Diabetes
NCT04854083 ·Status: UNKNOWN ·Phase: PHASE4
-
Impact of Semaglutide on CD34+ EPC and Fat Derived MSC
NCT04126603 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes
NCT05780905 ·Status: RECRUITING ·Phase: PHASE4
-
The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes
NCT01595789 ·Status: COMPLETED ·Phase: PHASE4
-
Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus
NCT06057077 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Semaglutide and Intestinal Iron Absorption
NCT06629688 ·Status: COMPLETED ·Phase: NA
-
Trial Investigating the Absorption, Metabolism and Excretion After a Single Subcutaneous Dose of [3H]-Semaglutide in Healthy Male Subjects
NCT02060266 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
NCT06323174 ·Status: COMPLETED ·Phase: PHASE3
-
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment
NCT07171723 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes
NCT07272343 ·Status: RECRUITING ·Phase: PHASE4
-
GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease
NCT06546384 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
NCT02655770 ·Status: COMPLETED ·Phase: PHASE4