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Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

NCT06295965 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2026-04-17

No results posted yet for this study

Summary

This study is being done to investigate clonal hematopoiesis and therapy-emergent myeloid neoplasms in patients with ovarian or other solid cancers. Researchers want to identify risk factors for developing these blood cancers as well as if there is/are a genetic/environmental component(s) to developing blood cancer.

Conditions

  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Ovarian Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
  • Recurrent Malignant Solid Neoplasm
  • Clonal Cytopenia of Undetermined Significance
  • Clonal Hematopoiesis
  • Idiopathic Cytopenia of Undetermined Significance
  • Non-Neoplastic Hematopoietic and Lymphoid Cell Disorder
  • Ovarian Carcinoma
  • Myeloid Neoplasm Post Cytotoxic Therapy

Interventions

OTHER

Non-Interventional Study

Non-interventional study

Sponsors & Collaborators

Principal Investigators

  • Elizabeth Swisher · Fred Hutch/University of Washington Cancer Consortium

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-02
Primary Completion
2028-12-31
Completion
2031-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06295965 on ClinicalTrials.gov