Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer
NCT06292286 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2025-06-11
Summary
About 80% of advanced ovarian cancer patients recurred in 2-3 years. Secondary cytoreduction benefits selected patients who have high chance of complete resection. Whether secondary interval surgery can be used at recurrence is not known.
Conditions
- Recurrent Ovarian Carcinoma
Interventions
- PROCEDURE
-
Carboplatin or cisplatin
Carboplatin of cisplatin for 3-6 cycles
- DRUG
-
Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar
Paclitaxel, gemcitabine or liposomal doxorubicin, for 3-6 cycles
- DRUG
-
Bevacizumab or biosimilar
Optional
- PROCEDURE
-
Cytoreductive surgery
Cytoreductive surgery after chemotherapy
Sponsors & Collaborators
-
The University of Hong Kong
lead OTHER
Principal Investigators
-
Ka Yu Tse · The University of Hong Kong
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Hong Kong
Study Locations
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