French Assessment of MRD by Liquid Biopsies in PDAC Patients (FRENCH.MRD.PDAC)
NCT06287749 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 37
Last updated 2025-07-10
Summary
The overall objective of this GUIDE.MRD consortium is to confirm that ctDNA detected after curative intended treatment for PDAC is a marker of residual disease and for risk-of-recurrence, and applicable in clinical practice.
Primary objective To confirm that ctDNA analyses performed after PDAC treatment can identify patients with a high risk-of-recurrence.
Specifically, the investigators want to determine the association between disease-free survival (DFS) and ctDNA detection status after
1. curative-intended surgery and
2. adjuvant chemotherapy.
FRENCH.MRD.PDAC is the French study of the european GUIDE.MRD project
Conditions
- Pancreatic Cancer Resectable
- Pancreatic Ductal Adenocarcinoma
- Minimal Residual Disease
- Liquid Biopsy
- ctDNA
Interventions
- BIOLOGICAL
-
Blood sample/Liquid Biopsy
ctDNA analysis
Sponsors & Collaborators
-
University Hospital, Montpellier
lead OTHER
Principal Investigators
-
Thomas BARDOL, M.D. · University Hospital, Montpellier
-
Catherine ALIX-PANABIERES, Ph.D. · University Hospital, Montpellier
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-03-01
- Primary Completion
- 2028-10-31
- Completion
- 2028-10-31
Countries
- France
Study Locations
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