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Registry of Haploidentical Hematopoietic Stem Cell Transplantation in Adult With Hematologic Disease

NCT06286228 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 43

Last updated 2024-03-01

No results posted yet for this study

Summary

The goal of this observational study is to register hematologic patients with haploidentical hematopoietic stem cell transplantation (haploHSCT). The main questions it aims to answer are:

* 1-year progression free survival rate
* 1-year overall survival rate
* Graft-versus-host free relapsed free survival at 30-day, 100-day, 180-day and 1-year
* Chronic Graft-versus-host free relapsed free survival at 180-day and 1-year
* Rate of Neutrophil and platelet engraftment
* Efficacy of donor specific antibody desensitization
* Relapsed rate
* Primary and late graft failure
* Safety and complication of haploHSCT
* Complication of viral, bacterial, and fungal infection
* Viral reactivation
* Comparison outcomes between matched sibling donor (MSD) HSCT and matched unrelated donor (MUD) HSCT
* Comparison cost-effectiveness of treatment between matched sibling donor (MSD) HSCT and matched unrelated donor (MUD) HSCT Participants will be collected the data of baseline diagnosis, treatment, treatment results of all admission and follow-up visits from hospital medical record.

Conditions

Sponsors & Collaborators

  • Siriraj Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-01
Primary Completion
2029-04-01
Completion
2030-04-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06286228 on ClinicalTrials.gov