The Effects of an Acute High-intensity Exercise on Heart and Brain Function in People With Spinal Cord Injury
NCT06274658 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2025-09-03
Summary
The heart and brain are regulated by the autonomic nervous system. Control of these organs can be disrupted in people with spinal cord injury (SCI). This may affect their ability to regulate blood pressure during daily activities and process the high-level information. Previous studies show that high-intensity exercise induces better outcomes on heart and information processing ability in non-injured people compared to moderate-intensity exercise. However, it is unknown the effects of high-intensity exercise on heart and brain function in people with SCI. Therefore, this study aims to examine the effects of a single bout of high-intensity interval training on heart and brain function in this people with SCI compared to age- and sex-matched non-injured controls.
Conditions
- Autonomic Nervous System Disease
- Spinal Cord Injuries
- Cognition
Interventions
- BEHAVIORAL
-
High-intensity interval exercise
Three high-intensity exercise bouts, each at 100% of maximal power output for 20 seconds, interspersed with active recovery periods of 120 seconds at 10% of maximal power output.
Sponsors & Collaborators
-
State University of New York at Buffalo
lead OTHER
Principal Investigators
-
Wenjie Ji, MS · University at Buffalo
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-02-14
- Primary Completion
- 2025-06-30
- Completion
- 2025-07-31
Countries
- United States
Study Locations
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