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Magnetic Localization of Sentinel Nodes in Squamous Cell Oral Carcinoma.

NCT06261983 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2024-02-15

No results posted yet for this study

Summary

Sentinel node biopsy has been shown to be a viable alternative to elective neck dissection in the early stages of squamous cell oral carcinoma. The aim of this study was to describe the magnetic localization of sentinel nodes (SN) after peritumoral injection of superparamagnetic iron oxide (SPIO) for treating this type of tumor and to analyze the technique's diagnostic performance in 23 patients. The technique located SNs (with minimal complication) in 95.6 % (22/23) of the patients. Three relapses occurred, one in a patient who had shown negative in magnetic SN location and elective neck dissection. The diagnostic performance of magnetic localization achieved a sensitivity and negative predictive value of 0.80 y 0.94, respectively. Magnetic localization of SNs has been shown to be a reproducible technique that may offer a viable alternative to the conventional technique.

Conditions

  • Diagnostic Value of Sentinel Node Biopsy Guided by Magnetic Probe

Interventions

PROCEDURE

Sentinel node biopsy guided by magnetic probe

Sentinel nodes exeresis guided by magnetic probe after injection submucosally and peritumorally of super-para-magnetic contrast. Standard neck dissection (levels I-II) were carry out after sentinel node biopsy

Sponsors & Collaborators

  • Hospital Donostia

    lead OTHER

Eligibility

Min Age
29 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06261983 on ClinicalTrials.gov