Study of Analgesic Action of Pregabalin, Duloxetine and Tramadol in Patients With Different Neuropathic Pain Phenotypes
NCT06252116 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2024-02-09
Summary
Chronic pain is the most frequent cause from which millions of patients suffer worldwide, which makes them unable to work but also greatly affects their quality of life. Chronic pain is a condition in itself. Neuropathic pain is a consequence of damage or disease of the peripheral or central nervous system and presents a heterogeneous clinical profile. A large number of pharmaceutical and non-pharmacological agents, as well as various complementary therapies, have been used in the treatment of neuropathic pain. However, their effectiveness is considered moderate and limited and is under investigation because a significant proportion of patients do not respond satisfactorily to treatment.
Purpose: The purpose of the study is to investigate the effectiveness of analgesics in the different phenotypes of neuropathic pain.
Conditions
- Neuropathic Pain
Interventions
- DRUG
-
Pregabalin group
Pregabalin group
- DRUG
-
Duloxetine group
Duloxetine group
Sponsors & Collaborators
-
Aristotle University Of Thessaloniki
lead OTHER
Principal Investigators
-
Ekaterini Amaniti, MD, PhD · AHEPA University Hospital of Thessaloniki, Greece
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-03-05
- Primary Completion
- 2024-07-20
- Completion
- 2024-09-07
- FDA Drug
- Yes
Countries
- Greece
Study Locations
More Related Trials
-
A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain
NCT01485094 ·Status: TERMINATED ·Phase: PHASE2
-
Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
NCT00740571 ·Status: UNKNOWN ·Phase: PHASE3
-
Pain Prevention and Treatment Through the Enhancement of the Anti-nociceptive Component of Pain Modulation Profiles
NCT02020122 ·Status: COMPLETED ·Phase: NA
-
Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male Volunteers
NCT01119222 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of the Analgesic Effects of PF-06372865 in Healthy Volunteers Using Evoked Pain Endpoints
NCT02238717 ·Status: COMPLETED ·Phase: PHASE1
-
Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain
NCT01302275 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Gabapentin and Pregabalin for Radicular Pain
NCT02064790 ·Status: COMPLETED
-
A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia
NCT00394901 ·Status: COMPLETED ·Phase: PHASE3
-
Mechanism-based Choice of Therapy for Neuropathic Pain
NCT01359514 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Pregabalin Versus Combined Pregabalin and Milnacipran in Fibromyalgia.
NCT03905486 ·Status: COMPLETED ·Phase: NA
-
The Effects of Pregabalin on Postoperative Pain After Cardiac Surgery
NCT01701921 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
P4 (Pregabalin for Peripheral Posttraumatic Pain)
NCT00292188 ·Status: COMPLETED ·Phase: PHASE4
-
Pain and Chronic Pancreatitis - Clinical End Experimental Studies
NCT00755573 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
NCT06091553 ·Status: RECRUITING ·Phase: PHASE2
-
The Clinical Effect of Pregabalin on Neuropathic Pain in Central Sensitized Patients After Total Knee Arthroplasty
NCT05254652 ·Status: UNKNOWN ·Phase: NA
-
Assessment of Peripheral GABA Receptors for Local Pain Relief
NCT02928328 ·Status: UNKNOWN ·Phase: NA
-
Imipramine and Pregabalin Combination in Painful Polyneuropathy
NCT01047488 ·Status: UNKNOWN ·Phase: PHASE4
-
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
NCT06155916 ·Status: RECRUITING ·Phase: NA
-
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
NCT00403780 ·Status: TERMINATED ·Phase: PHASE4
-
A Study To Assess The Ability Of A Crossover Study Design To Detect The Efficacy Of Pregabalin In Post-Traumatic Neuropathic Pain Patients
NCT00654940 ·Status: COMPLETED ·Phase: PHASE1
-
The Efficacy and Safety of Pregabalin and Crisugabalin in Patients With Fibromyalgia
NCT07196657 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Perioperative Pregabalin in Reducing the Incidence of Chronic Neuropathic Pain and Postthoracotomy Syndrome.
NCT00967135 ·Status: COMPLETED ·Phase: NA
-
Chronic Pain Management After Herniorraphy
NCT00772291 ·Status: COMPLETED ·Phase: PHASE3
-
Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain
NCT01701362 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment
NCT01713426 ·Status: COMPLETED ·Phase: PHASE4