Effect of Different Frequencies of Umbilical Cord-mesenchymal Stem Cells Through Peripheral Vein in Patients With ESLD
NCT06242405 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92
Last updated 2026-03-31
Summary
Stem cells are non-terminal cells that can self renew and replicate through symmetric or asymmetric division, with the potential to differentiate into different types of cells and tissues. Multiple studies have shown that mesenchymal stem cell has good safety and effectiveness in improving acute or chronic liver injury. Randomized controlled trials have confirmed the efficacy of single infusion of stem cells in treating ESLD. It seems that the multiple infusion is better than single infusion.
Conditions
- End-Stage Liver DIsease
Interventions
- BIOLOGICAL
-
umbilical cord-mesenchymal stem cells
Umbilical cord mesenchymal stem cells injected through peripheral veins
Sponsors & Collaborators
-
General Hospital of Shenyang Military Region
lead OTHER
Principal Investigators
-
Xingshun Qi, MD · The General Hospital of Northern Theater Command
-
Wen Ning, MM · The General Hospital of Northern Theater Command
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-03-05
- Primary Completion
- 2025-12-30
- Completion
- 2025-12-30
Countries
- China
Study Locations
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