Trial Outcomes & Findings for Nudging Patients to Increase Shingles Vaccination (NCT NCT06238726)
NCT ID: NCT06238726
Last Updated: 2026-08-14
Results Overview
Received a first Shingrix vaccination on the appointment date (y/n)
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
50786 participants
Primary outcome timeframe
3 days after enrollment
Results posted on
2026-08-14
Participant Flow
Participant milestones
| Measure |
No Intervention : Passive Control
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Overall Study
STARTED
|
10172
|
10103
|
10173
|
10161
|
10177
|
|
Overall Study
COMPLETED
|
10172
|
10103
|
10173
|
10161
|
10177
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
0
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Baseline characteristics by cohort
| Measure |
No Intervention : Passive Control
n=10172 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=10103 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=10173 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=10161 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=10177 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Total
n=50786 Participants
Total of all reporting groups
|
|---|---|---|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
0 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
0 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
0 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
0 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
0 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Age, Categorical
Between 18 and 65 years
|
5810 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5823 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5840 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5925 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5812 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
29210 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Age, Categorical
>=65 years
|
4362 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4280 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4333 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4236 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4365 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
21576 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Sex: Female, Male
Female
|
5640 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5542 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5623 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5569 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
5664 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
28038 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Sex: Female, Male
Male
|
4532 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4561 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4550 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4592 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
4513 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
22748 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
22 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
12 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
15 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
16 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
11 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
76 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
Asian
|
97 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
90 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
71 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
95 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
69 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
422 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
31 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
27 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
18 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
30 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
23 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
129 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
Black or African American
|
304 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
291 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
272 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
311 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
331 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
1509 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
White
|
9496 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
9461 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
9577 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
9471 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
9535 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
47540 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
More than one race
|
36 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
37 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
40 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
46 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
34 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
193 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
186 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
185 Participants
n=11 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
180 Participants
n=22 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
192 Participants
n=255 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
174 Participants
n=83 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
917 Participants
n=84 Participants • For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
388 Participants
n=11 Participants
|
401 Participants
n=11 Participants
|
370 Participants
n=22 Participants
|
375 Participants
n=255 Participants
|
388 Participants
n=83 Participants
|
1922 Participants
n=84 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
9528 Participants
n=11 Participants
|
9435 Participants
n=11 Participants
|
9540 Participants
n=22 Participants
|
9529 Participants
n=255 Participants
|
9549 Participants
n=83 Participants
|
47581 Participants
n=84 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
256 Participants
n=11 Participants
|
267 Participants
n=11 Participants
|
263 Participants
n=22 Participants
|
257 Participants
n=255 Participants
|
240 Participants
n=83 Participants
|
1283 Participants
n=84 Participants
|
PRIMARY outcome
Timeframe: 3 days after enrollmentPopulation: For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Received a first Shingrix vaccination on the appointment date (y/n)
Outcome measures
| Measure |
No Intervention : Passive Control
n=9851 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=9816 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=9850 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=9841 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=9839 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Shingrix Vaccination on Appointment Day
|
272 Participants
|
452 Participants
|
479 Participants
|
480 Participants
|
460 Participants
|
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 10 days following enrollmentReceived a first Shingrix vaccination in the 10 days following enrollment (y/n)
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: 3 days after enrollmentAttended the target Shingrix-eligible appointment (y/n)
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 14 months following enrollmentReceived a first Shingrix vaccination in the 14 months following enrollment (y/n)
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 14 months following enrollmentNumber of days between enrollment and first Shingrix vaccination
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 14 months following enrollmentCompleted Shingrix vaccination series by getting a second Shingrix vaccination (y/n)
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 14 months following enrollmentNumber of days between first and second Shingrix vaccination
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: In the 14 months following enrollmentDiagnosed with shingles (y/n)
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: 3 days after enrollmentPopulation: For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Received a first Shingrix vaccination on the appointment date (y/n) by age group
Outcome measures
| Measure |
No Intervention : Passive Control
n=9851 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=9816 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=9850 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=9841 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=9839 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Shingrix Vaccination on Appointment Day by Age Group
19 years to 64 years
|
193 Participants
|
304 Participants
|
324 Participants
|
353 Participants
|
304 Participants
|
|
Shingrix Vaccination on Appointment Day by Age Group
≥ 65 years
|
79 Participants
|
148 Participants
|
155 Participants
|
127 Participants
|
156 Participants
|
|
Shingrix Vaccination on Appointment Day by Age Group
≤ 18 years
|
0 Participants
|
0 Participants
|
0 Participants
|
0 Participants
|
0 Participants
|
OTHER_PRE_SPECIFIED outcome
Timeframe: 3 days after enrollmentPopulation: For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Received a first Shingrix vaccination on the appointment date (y/n) by sex
Outcome measures
| Measure |
No Intervention : Passive Control
n=9851 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=9816 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=9850 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=9841 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=9839 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Shingrix Vaccination on Appointment Day by Sex
Female
|
142 Participants
|
252 Participants
|
257 Participants
|
258 Participants
|
227 Participants
|
|
Shingrix Vaccination on Appointment Day by Sex
Male
|
130 Participants
|
200 Participants
|
222 Participants
|
222 Participants
|
233 Participants
|
OTHER_PRE_SPECIFIED outcome
Timeframe: 3 days after enrollmentPopulation: For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Received a first Shingrix vaccination on the appointment date (y/n) by race
Outcome measures
| Measure |
No Intervention : Passive Control
n=9851 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=9816 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=9850 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=9841 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=9839 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Shingrix Vaccination on Appointment Day by Race
American Indian or Alaska Native
|
0 Participants
|
1 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
Asian
|
7 Participants
|
4 Participants
|
9 Participants
|
9 Participants
|
4 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
Native Hawaiian or Other Pacific Islander
|
0 Participants
|
1 Participants
|
1 Participants
|
2 Participants
|
2 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
Black or African American
|
9 Participants
|
6 Participants
|
12 Participants
|
11 Participants
|
8 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
White
|
249 Participants
|
427 Participants
|
443 Participants
|
446 Participants
|
439 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
More than one race
|
2 Participants
|
2 Participants
|
5 Participants
|
2 Participants
|
1 Participants
|
|
Shingrix Vaccination on Appointment Day by Race
Unknown or Not Reported
|
5 Participants
|
11 Participants
|
8 Participants
|
10 Participants
|
6 Participants
|
OTHER_PRE_SPECIFIED outcome
Timeframe: 3 days after enrollmentPopulation: For the primary analysis, one patient per phone number was included to preserve independence of observations since randomization occurred on the phone number level. If a phone number was associated with more than one enrolled patient, we prioritized the first patient enrolled if enrollment dates differed, GHP members if enrolled on the same day and GHP membership differed, or selected a patient randomly if all shared the same enrollment date and GHP membership status.
Received a first Shingrix vaccination on the appointment date (y/n) by ethnicity
Outcome measures
| Measure |
No Intervention : Passive Control
n=9851 Participants
Patients in this arm will not be sent any messages.
|
Active Comparator : Active Control
n=9816 Participants
Patients in this arm will be sent messages encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk
n=9850 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : Multi-fact
n=9841 Participants
Patients in this arm will be sent messages with facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
Experimental : High Risk + Multi-fact
n=9839 Participants
Patients in this arm will be sent messages informing them that they are at high risk for shingles because they are ages 50+, with additional facts about shingles and Shingrix, and encouraging them to ask about Shingrix at their upcoming appointment.
|
|---|---|---|---|---|---|
|
Shingrix Vaccination on Appointment Day by Ethnicity
Hispanic or Latino
|
5 Participants
|
16 Participants
|
11 Participants
|
21 Participants
|
18 Participants
|
|
Shingrix Vaccination on Appointment Day by Ethnicity
Not Hispanic or Latino
|
264 Participants
|
421 Participants
|
453 Participants
|
448 Participants
|
437 Participants
|
|
Shingrix Vaccination on Appointment Day by Ethnicity
Unknown or Not Reported
|
3 Participants
|
15 Participants
|
15 Participants
|
11 Participants
|
5 Participants
|
Adverse Events
Passive Control
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Active Control
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
High Risk
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Multi-fact
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
High Risk + Multi-fact
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place