Outcome of 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism

Summary

To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)

Conditions

• Primary Aldosteronism

Interventions

DIAGNOSTIC_TEST

68Ga-Pentixafor PET/CT

The patients had a normal diet with no special preparation before 68Ga-Pentixafor PET/CT imaging. The dosage of intravenously injected 68Ga-Pentixafor was calculated based on the patient's weight (1.85 MBq \[0.05mCi\]/kg). Local PET/CT scanning of the upper abdomen was performed on a hybrid PET/CT scanner at 10 minutes after the injection of the intravenous tracer, respectively.

Sponsors & Collaborators

• The Affiliated Hospital Of Southwest Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Tongji Hospital

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

  collaborator OTHER

• The Third Xiangya Hospital of Central South University

  collaborator OTHER

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• Changzhi Medical College

  collaborator OTHER

• Xiangya Hospital of Central South University

  collaborator OTHER

• Qifu Li

  lead OTHER

Principal Investigators

• Qifu Li, PhD · the Chongqing Primary Aldosteronism Study (CONPASS) Group

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-01-09

Primary Completion

2026-12-31

Completion

2027-12-31

Countries

• China

Study Locations