ctDNA and MRI Parameters in Head and Neck Cancer
NCT06215612 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2024-01-22
Summary
Patients undergoing primary radiochhemotherapy for locally advanced head and neck squamous cell carcinomas are included in this study. In addition to standard of care treatment patients will undergo addiational blood draws and MR imaging studies. Circulating cell free tumor DNA will be analysed in the blood samples. BIological data, imaging data and clinical data (such as patient and tumor characteristics, oncologic outcome, side effects) will be analysed in a biomathematical modelling approach.
Conditions
- Head and Neck Neoplasms
- Carcinoma, Squamous
Interventions
- OTHER
-
Blood draw, MRI
Blood draw, MRI
Sponsors & Collaborators
-
Franziska Eckert
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-29
- Primary Completion
- 2027-02-28
- Completion
- 2030-02-28
More Related Trials
-
Randomized Phase II Study of DCE-MRI-based Dose Escalation for Poor-prognosis and Neck Cancer
NCT02031250 ·Status: COMPLETED ·Phase: PHASE2
-
Chemo-Radiotherapy Boost Treatment Guided by Perfusion MRI on Hypoxic Zones in Head and Neck Cancer
NCT06880289 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Radiotherapy With Pembrolizumab in Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
NCT03386357 ·Status: TERMINATED ·Phase: PHASE2
-
Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer
NCT02388932 ·Status: TERMINATED ·Phase: NA
-
RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer
NCT00956007 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Observational Study on Biomarkers in Head and Neck Cancer (HNprädBio)
NCT02059668 ·Status: COMPLETED
-
MRI in Finding Hypoxia in Patients Undergoing Chemo and Radiation for Head and Neck Cancer
NCT00896350 ·Status: TERMINATED ·Phase: PHASE1
-
Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
NCT00652613 ·Status: UNKNOWN ·Phase: PHASE2
-
Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and Neck
NCT05291663 ·Status: UNKNOWN
-
Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer
NCT01126216 ·Status: TERMINATED ·Phase: PHASE3
-
Chemotherapy Plus Radiation Therapy in Treating Patients With Squamous Cell Cancer of the Head and Neck
NCT00003200 ·Status: COMPLETED ·Phase: PHASE1
-
Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer
NCT00721513 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of SBRT and Docetaxel for Locally Recurrent or Second Primary Squamous Cell Carcinoma of the Head and Neck
NCT02110992 ·Status: TERMINATED ·Phase: PHASE1
-
Durvalumab, Cetuximab and Radiotherapy in Head Neck Cancer
NCT03051906 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC
NCT02047201 ·Status: COMPLETED ·Phase: PHASE2
-
Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC
NCT00158652 ·Status: COMPLETED ·Phase: PHASE3
-
Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer
NCT00085631 ·Status: TERMINATED ·Phase: PHASE3
-
Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas
NCT02279459 ·Status: COMPLETED
-
Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy
NCT05992610 ·Status: RECRUITING ·Phase: NA
-
Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer
NCT06529809 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
NCT00006107 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Treatment Patterns and Clinical Outcomes in First Line Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (1L R/M SCCHN) Participants in Europe
NCT05123950 ·Status: COMPLETED
-
Predicting Immunotherapy Efficacy in Head and Neck Squamous Cell Cancer
NCT05296135 ·Status: WITHDRAWN
-
Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma
NCT03422536 ·Status: COMPLETED ·Phase: PHASE2
-
Adjuvant Cetuximab and Chemoradiation in Head and Neck Cancer
NCT00791141 ·Status: COMPLETED ·Phase: PHASE2