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EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

NCT06212791 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-03-12

No results posted yet for this study

Summary

Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).

Conditions

  • Paroxysmal Atrial Fibrillation

Interventions

BEHAVIORAL

Self- Report Evaluation-Duke Activity Status Index

Complete the Self- Report Evaluation-Duke Activity Status Index

BEHAVIORAL

Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire

Complete the Self- Report Evaluation, Atrial Fibrillation Effect on Quality of Life Questionnaire

DIAGNOSTIC_TEST

Cardiopulmonary exercise test (CPET)

Cardiopulmonary exercise test (CPET)

DIAGNOSTIC_TEST

Transthoracic echocardiogram

Transthoracic echocardiogram at rest and immediately following peak exercise during CPET

DIAGNOSTIC_TEST

Ambulatory cardiac rhythm assessment

Ambulatory cardiac rhythm assessment

DIAGNOSTIC_TEST

Cardiovascular magnetic resonance (CMR)

Cardiovascular magnetic resonance (CMR) study at rest and during two stages of submaximal exercise (ExeCMR)

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Virginia Commonwealth University

    lead OTHER

Principal Investigators

  • Cory Trankle · Virginia Commonwealth University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-26
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06212791 on ClinicalTrials.gov