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ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery

NCT06204835 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2024-05-22

No results posted yet for this study

Summary

In this study, the investigators will detect hepatocellular carcinoma lesions using fluoescence imaging with ITGA6 targeting probes during tumor resection surgery. The aim is to evaluate wether intraoperative fluorescence imaging targeting ITGA6 can help to improve the detction effect of hepatocellular carcinoma, and finally help the accurate surgical resection.

The main purposes of this study include:

1. To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the ITGA6 targeting probe.
2. To validate the safety and effectiveness of the proposed ITGA6 targeting probes for clinical application.

Conditions

Interventions

DRUG

RD-Cy7 fluorophore

Fluorophore targeting ITGA6 that is overexpressed in HCC cells

Sponsors & Collaborators

  • Institute of Automation, Chinese Academy of Sciences

    lead OTHER

Principal Investigators

  • Zhenhua Hu, Ph. D · Institute of Automation, Chinese Academy of Sciences

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-07
Primary Completion
2034-12-31
Completion
2039-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06204835 on ClinicalTrials.gov