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Impact of Exercise on Immune System and Metabolism in Football Players

NCT06201052 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2024-07-10

No results posted yet for this study

Summary

Physical exercise, especially of high intensity, is a significant burden to the athlete's body. It should be emphasized that achieving high results in competitive sports requires significant, sometimes extreme, exercise loads during training, which may result in homeostasis disorders, adversely affecting athletes' fitness. Intense and prolonged physical exercise elevates reactive oxygen species, potentially impacting immune function. The mechanism, particularly in high-intensity activities, remains incompletely understood. Excessive oxygen radicals may induce metabolic changes, causing rapid erythrocyte damage and elevated redox-active free iron. This iron increase can be harmful, increasing oxidative stress and immune system activation. The sustained negative impact that may be observed even during post-workout recovery needs further exploration.

"This study aims to explain the impact of an intense exercise test on the immune system, pro-antioxidant balance, and iron metabolism in athletes with varying training levels. The primary questions it seeks to address are:

1. How do athletes' experience and training background influence the immune system's response, pro-antioxidant balance, and iron regulation?
2. Can the level of adaptation to physical exercise (training status) affect the rate of regeneration and the time required to return to pre-exercise homeostasis?"

Conditions

  • Healthy

Interventions

OTHER

Exercise test

Beep Test for measuring aerobic power

Sponsors & Collaborators

  • Nicolaus Copernicus University

    collaborator OTHER

  • Poznan University of Physical Education

    lead OTHER

Principal Investigators

  • Joanna Ostapiuk-Karolczuk, Ph.D. · Poznan University of Physical Education

Eligibility

Min Age
22 Years
Max Age
37 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2018-05-10
Completion
2018-11-15

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06201052 on ClinicalTrials.gov