Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

NCT06181812 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 332

Last updated 2026-04-08

No results posted yet for this study

Summary

The goal of this observational study is to describe the prevalence of germ line-pathogenic variants in Mexican patients with lung adenocarcinoma.

The main questions it aims to answer are:

1. What is the prevalence of pathogenic variants in genes associated with lung adenocarcinoma in Mexican patients younger than fifty?
2. Which clinical-pathological characteristics are associated with germ-line pathogenic variants in patients with lung adenocarcinoma?
3. How actionable somatic mutations are associated with germ line-pathogenic variants of patients with lung adenocarcinoma?

Participants will be asked to sign an informed consent; after that, they will be instructed to donate 10 ml of peripheral blood by venipuncture in the morning and before the patient has taken morning medication and the first meal, following a period of 8-12 hr fasting.

Conditions

Sponsors & Collaborators

  • Oscar Gerardo Arrieta Rodríguez

    lead OTHER

Principal Investigators

  • Oscar G Arrieta Rodriguez, M.D., M.Sc. · Instituto Nacional de Cancerologia de Mexico

Eligibility

Min Age
16 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-12-15
Primary Completion
2026-12-15
Completion
2027-12-15

Countries

  • Mexico

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06181812 on ClinicalTrials.gov