Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumab
NCT06167642 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2025-06-06
Summary
This study aims to assess whether, and the degree to which, ofatumumab modulates or reduces rates of retinal atrophy in people with relapsing-remitting MS (RMS), according to baseline serum neurofilament light chain (sNfL) levels.
Conditions
- Multiple Sclerosis
- Tomography, Optical Coherence
- Retinal Degeneration
- Visual Acuity
Interventions
- DRUG
-
Ofatumumab
Ofatumumab therapy is part of the patient's clinical care and is not given as part of the study
Sponsors & Collaborators
- collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Shiv Saidha, MBBCh · Johns Hopkins University
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-22
- Primary Completion
- 2027-03-31
- Completion
- 2027-03-31
Countries
- United States
Study Locations
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