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Influence of Pupillary Behavior During Eye Surgery on Morphological and Functional Outcome

NCT06160960 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-12-07

No results posted yet for this study

Summary

Pupillary movement during eye surgery can be a challenge for eye surgeons. Despite the risk of intraocular lens damage and malpositioning due to mechanical manipulation1, iris manipulation may lead to a significant elevation of cytokines in the aqueous humor and an increase of postoperative inflammation2, 3. Iris damage is also known to lead to an increase of prostaglandin production which will not only lead to an increase of inflammation but also has an impact on intraoperative miosis4. This leads to the assumption that postoperative inflammation can be related to intraoperative pupillary movements due to the same leading cause of an increase of inflammatory mediators. Tracking intraoperative pupillary movements might therefore be a helpful tool for the prediction of postoperative PCME and could have an impact on therapeutic decisions after surgery.

Conditions

  • Cataract
  • Corneal Disease
  • Vitreous Disorder

Interventions

OTHER

OCT Scan, Video of pupil movement, video of toric lens

A picture of the central macular area is taken, video of pupil movment, video of toric lens rotation.

Sponsors & Collaborators

  • University of Klagenfurt

    collaborator OTHER

  • Klinikum Klagenfurt am Wörthersee

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-09
Primary Completion
2024-10-01
Completion
2024-10-01

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06160960 on ClinicalTrials.gov