Cognitive Effects of tDCS and tRNS in Schizophrenia

NCT06155786 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-03-18

No results posted yet for this study

Summary

The purpose of this study is to investigate the cognitive effects of different electrical stimulation modalities, such as transcranial direct and random-noise stimulation over the dorsolateral prefrontal cortex, in schizophrenia.

Conditions

Interventions

DEVICE

transcranial direct current stimulation (tDCS) active stimulator

In tDCS the electrical current is applied directly between electrodes mounted on the head which can can de-or hyperpolarizes resting membrane potential and thereby modulate cortical excitability

DEVICE

transcranial random noise stimulation (tRNS)

Here, an alternating electrical current is applied at a mix of frequencies it is called transcranial random noise stimulation (tRNS), which can be delivered in low (between 0.1-100 Hz) or high (between 101-640 Hz) frequency stimulation

DEVICE

transcranial direct current stimulation (tDCS) sham stimulator

Here a sham electrical current is applied directly between electrodes mounted on the head which can can de-or hyperpolarizes resting membrane potential and thereby modulate cortical excitability

Sponsors & Collaborators

  • Leibniz Research Centre for Working Environment and Human Factors

    collaborator OTHER
  • Payame Noor University

    collaborator UNKNOWN
  • RWTH Aachen University

    collaborator OTHER
  • The National Brain Mapping Laboratory (NBML)

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-11-01
Completion
2024-07-22

Countries

  • Iran

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06155786 on ClinicalTrials.gov