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Risk of NSAIDs on Anastomotic Leak for Rectal Surgery

NCT06155175 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1969

Last updated 2025-05-07

No results posted yet for this study

Summary

Conflicting reports of the association between early postoperative non-steroidal anti-inflammatory drugs (NSAIDs) administration and anastomotic leak (AL) after rectal surgery have continued. The definition of AL and the exposure of NSAIDs differ from each other among studies, which may result in the different conclusions.

The aim of this retrospective study was to clarify the effect of NSAIDs on anastomotic leak from new angels.

Conditions

  • Anastomotic Leak
  • Anti-Inflammatory Agents, Non-Steroidal

Interventions

DRUG

NSAIDs

The exposure to NSAIDs: NSAIDs was used at least once within the first day after surgery

Sponsors & Collaborators

  • Third Military Medical University

    lead OTHER

Principal Investigators

  • WeiDong Tong, MD · Department of General Surgery, Daping Hospital, Army Medical University, Chongqing 400042, China

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2023-12-31
Completion
2024-02-25

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06155175 on ClinicalTrials.gov