MedTrace Logo

Investigation of Immune Amnesia Following Measles Infection in Select African Regions

NCT06153979 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 264

Last updated 2026-05-12

No results posted yet for this study

Summary

The goal of this observational study is to investigate the effects of measles virus (MeV) infection on pre-existing immunity, vaccine response, and susceptibility to subsequent illness in children aged 1-15 either with or without acute MeV infection.

Conditions

  • Measles Infection

Interventions

BIOLOGICAL

Verorab

Participants in each group will receive rabies vaccination (standard 3-dose series given as PrEP), with the first dose randomized to either Week 8 or Week 47 after enrollment.

Sponsors & Collaborators

Principal Investigators

  • Sally Hunsberger, Ph.D. · National Institute of Allergy and Infectious Diseases (NIAID)

Eligibility

Min Age
1 Year
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-16
Primary Completion
2026-04-16
Completion
2026-04-16

Countries

  • Guinea
  • Mali

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06153979 on ClinicalTrials.gov